Coronavirus Q&A: Critical Care Update

COVID-19 Critical Care Update with Maurizio Cecconi, MD of Humanitas University in Milan and Derek C. Angus, MD, MPH of the University of Pittsburgh. Recorded on June 8, 2020. • Earn Free CME credits by watching JAMA Livestreams and completing a brief questionnaire. Claim 0.5 credits for each video at https://ja.ma/covidqa • Coronavirus Resource page from the JAMA Network: https://ja.ma/covidyt ===================================================================== To watch all the #JAMALive Q&A's Visit: https://ja.ma/covidqaytpl Don't forget to hit subscribe or click https://ja.ma/subscribe #JAMALive #Coronavirus #SARSCoV2 --------------------------------------------------------------------------------- For more from JAMA • https://www.jama.com • https://www.facebook.com/JAMAJournal • https://www.twitter.com/JAMA_Current • https://www.linkedin.com/company/jamanetwork Follow the #JAMANetwork • https://www.jamanetwork.com • http://www.jamanetworkaudio.com • https://www.facebook.com/JAMANetwork • https://www.twitter.com/JAMANetwork • https://www.instagram.com/JAMANetwork • https://www.pinterest.com/JAMANetwork Topics discussed in this interview: 0:00 Introduction 1:34 Anything new about epidemiology of COVID-19? What's the major risk characteristics, risk factors? What's the mortality look like in the intensive care unit? 4:33 What is the mortality rate in the ICU run by Dr Angus in Pittsburgh? 5:58 Is smoking or asthma is protective? 11:45 Where are we on respiratory support? High-flow oxygen, prone positioning, preventing intubation? Is early intubation better than late intubation? 14:52 Prone positioning prior to intubation? 16:23 Approach to respiratory support 21:22 Are there phenotypes and should phenotypes drive therapy? (Treatments) 30:13 Is it going to take more than one drug to really reduce mortality? Is it convalescent plasma and steroids? Is it Tocilizumab and steroids? 33:13 Do you think it's some form of two drugs? Is it earlier treatment with some drug regimen? 35:19 Convalescent plasma as a treatment as compared to Remdesivir? 37:19 Does the morbidity associated with COVID-19, following being in the ICU look different to you than any other frail, elderly individual who is in the ICU and is either intubated or not? Do they need a different type of post-ICU care? 42:17 From a critical care standpoint, what have been the biggest surprises from this pandemic? What scientific questions do we still need to answer? 50:27 Closing notes

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